Endovita E-Se Inj

Description

Composition: 

Each 1 ml contains: 

Vitamin E : 80 mg 

Sodium selenite : 1.6 mg 

Properties: 

• Vitamin E is an antioxidant and is necessary for the stability and function of muscle tissues.   
• Selenium: The essential role of selenium is as part of the enzyme glutathione peroxidase, whose function is to prevent free-radical damage to tissue. 
• There is a complex interaction between the requirements of selenium and vitamin E whereby either may substitute in part for the other.  A deficiency is most frequently seen in young, fast growing animals, causing degeneration of cardiac, respiratory and skeletal muscles and neurone degeneration in horses. 

Indications: 

Prophylactic indications: 

On farms in known selenium-deficient soil areas. 

When diets low in vitamin E are fed, e.g. diets containing high levels of moist stored grain or maize silage. 

On farms where there is a history of vitamin E and/or selenium deficiency, as may be indicated by poor breeding performance, excessive transport stress, or nutritional muscular dystrophy (in young animals on turning out to grass). 

To provide extra vitamin E during periods of heavy work-load (horses). 

Therapeutic indications: 

For the treatment of the various manifestations of nutritional muscular dystrophy (white muscle disease, nutritional myopathy) affecting cardiac and/or skeletal muscles, and associated symptoms. 

Dosage and administration: 

For administration by intramuscular or subcutaneous injection in cattle and sheep, and by intramuscular injection in the horse. 

Adult animals: 

Prophylaxis 1 ml per 27 kg bodyweight 

One injection at intervals of 3 months. 

Treatment 1 ml per 16 kg bodyweight 

Injections may be repeated at weekly intervals if necessary. 

Horses Up to 37.5 ml 

Cattle Up to 28 ml 

Sheep Up to 9.4 ml  

Young animals: 

Foals, calves 3.75 – 9.4 ml 

Lambs 0.9 – 5.6 ml 

Precautions: 

• Chronic administration of selenium has been shown to cause adverse fertility and fetal effects, but at the proposed frequency of dosing, every 1 – 12 weeks, these are not considered relevant.  Anaphylactic type reactions have been reported in pregnant cattle. 

• Do not overdose. 

Withdrawal period: 

Cattle and sheep: 

Meat: Zero day. 

Milk: Zero hour. 

Horses: 

Not to be used in horses intended for human consumption. 

 Storage:  

• Store in a dark and dry place at a temperature below 30oC.